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PRAMEF18 PRAME family member 18 [ Homo sapiens (human) ]

Gene ID: 391003, updated on 21-Dec-2023

Summary

Official Symbol
PRAMEF18provided by HGNC
Official Full Name
PRAME family member 18provided by HGNC
Primary source
HGNC:HGNC:30693
See related
Ensembl:ENSG00000279804 AllianceGenome:HGNC:30693
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
1p36.21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13222695..13226154, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12519546..12523005)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (13035499..13039011)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 9 Neighboring gene PRAME family member 13 Neighboring gene PRAME family member 31, pseudogene Neighboring gene PRAME family member 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
PRAME family member 18
Names
PRAME family member-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099850.2NP_001093320.2  PRAME family member 18

    Status: INFERRED

    Source sequence(s)
    AC244216
    Consensus CDS
    CCDS41258.2
    UniProtKB/Swiss-Prot
    Q5VWM3
    UniProtKB/TrEMBL
    A0A140TA27
    Related
    ENSP00000485473.2, ENST00000624297.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    13222695..13226154 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132914.1 Reference GRCh38.p14 PATCHES

    Range
    377035..380494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_015495298.1 Reference GRCh38.p14 PATCHES

    Range
    188463..191975 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187517.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    166163..169622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    12519546..12523005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001024659.1: Suppressed sequence

    Description
    NM_001024659.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.