U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR11G2 olfactory receptor family 11 subfamily G member 2 [ Homo sapiens (human) ]

Gene ID: 390439, updated on 26-Oct-2022

Summary

Official Symbol
OR11G2provided by HGNC
Official Full Name
olfactory receptor family 11 subfamily G member 2provided by HGNC
Primary source
HGNC:HGNC:15346
See related
Ensembl:ENSG00000196832 AllianceGenome:HGNC:15346
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR14-34
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR11G2 in Genome Data Viewer
Location:
14q11.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (20190896..20201075)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (14385654..14395830)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20659055..20669234)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily G member 1 pseudogene Neighboring gene olfactory receptor family 11 subfamily P member 1 pseudogene Neighboring gene olfactory receptor family 11 subfamily H member 5 pseudogene Neighboring gene olfactory receptor family 11 subfamily H member 6

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 11G2
Names
olfactory receptor OR14-34

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005503.2NP_001005503.2  olfactory receptor 11G2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, coding) represents the protein-coding allele encoded by the GRCh38 reference genome.
    Source sequence(s)
    AL163152, AL356019
    Consensus CDS
    CCDS32032.2
    UniProtKB/TrEMBL
    A0A126GWS8
    Related
    ENSP00000493171.1, ENST00000641682.1
    Conserved Domains (1) summary
    cd15913
    Location:29298
    7tmA_OR11G-like; olfactory receptor OR11G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001386033.1NP_001372962.1  olfactory receptor 11G2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2, coding) represents the protein-coding allele encoded by the GRCh38 reference genome.
    Source sequence(s)
    AL163152, AL356019
    Consensus CDS
    CCDS32032.2
    UniProtKB/TrEMBL
    A0A126GWS8
    Related
    ENSP00000493427.1, ENST00000641879.2
    Conserved Domains (1) summary
    cd15913
    Location:29298
    7tmA_OR11G-like; olfactory receptor OR11G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. NR_178048.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, non-coding) uses the same exon combination as variant 1, coding but represents the allele encoded by the T2T-CHM13v2.0 genome assembly. This variant is represented as non-coding because a frameshift in the C-terminus results in a premature stop codon.
    Source sequence(s)
    CP068264
  2. NR_178049.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2, non-coding) uses the same exon combination as variant 2, coding but represents the allele encoded by the T2T-CHM13v2.0 genome assembly. This variant is represented as non-coding because a frameshift in the C-terminus results in a premature stop codon.
    Source sequence(s)
    CP068264

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    20190896..20201075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791796.1 Reference GRCh38.p14 PATCHES

    Range
    393577..403756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    14385654..14395830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)