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OR56A5 olfactory receptor family 56 subfamily A member 5 [ Homo sapiens (human) ]

Gene ID: 390084, updated on 22-Sep-2022

Summary

Official Symbol
OR56A5provided by HGNC
Official Full Name
olfactory receptor family 56 subfamily A member 5provided by HGNC
Primary source
HGNC:HGNC:14792
See related
Ensembl:ENSG00000188691 AllianceGenome:HGNC:14792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR56A5P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Mar 2009]
Orthologs
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Genomic context

See OR56A5 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5967553..5968494, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6026055..6026996, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5988783..5989724, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268071 Neighboring gene olfactory receptor family 52 subfamily E member 5 Neighboring gene olfactory receptor family 52 subfamily Q member 1 pseudogene Neighboring gene olfactory receptor family 56 subfamily A member 3 Neighboring gene uncharacterized LOC124902621 Neighboring gene olfactory receptor family 52 subfamily L member 1

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 56A5
Names
olfactory receptor, family 56, subfamily A, member 5 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146033.1NP_001139505.1  olfactory receptor 56A5

    See identical proteins and their annotated locations for NP_001139505.1

    Status: VALIDATED

    Source sequence(s)
    AC025016
    Consensus CDS
    CCDS73248.1
    UniProtKB/Swiss-Prot
    P0C7T3
    UniProtKB/TrEMBL
    A0A126GWP3
    Related
    ENSP00000481594.1, ENST00000532411.2
    Conserved Domains (2) summary
    pfam00001
    Location:45295
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:45310
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    5967553..5968494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6026055..6026996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)