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OR52N2 olfactory receptor family 52 subfamily N member 2 [ Homo sapiens (human) ]

Gene ID: 390077, updated on 27-Nov-2024

Summary

Official Symbol
OR52N2provided by HGNC
Official Full Name
olfactory receptor family 52 subfamily N member 2provided by HGNC
Primary source
HGNC:HGNC:15228
See related
Ensembl:ENSG00000180988 AllianceGenome:HGNC:15228
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-57
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OR52N2 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5808924..5821483)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (5866715..5879282)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5830154..5842713)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 52 subfamily N member 1 Neighboring gene olfactory receptor family 52 subfamily N member 3 pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr11:5847231-5847800 Neighboring gene olfactory receptor family 52 subfamily E member 6 Neighboring gene olfactory receptor family 52 subfamily E member 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 52N2
Names
olfactory receptor OR11-57

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005174.3NP_001005174.1  olfactory receptor 52N2

    See identical proteins and their annotated locations for NP_001005174.1

    Status: VALIDATED

    Source sequence(s)
    AC131574
    Consensus CDS
    CCDS31399.1
    UniProtKB/Swiss-Prot
    B9EIL8, Q6IFF9, Q8NGI0
    UniProtKB/TrEMBL
    A0A126GWF5
    Related
    ENSP00000322801.2, ENST00000317037.3
    Conserved Domains (2) summary
    pfam00001
    Location:43295
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:33311
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    5808924..5821483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    5866715..5879282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)