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PROB1 proline rich basic protein 1 [ Homo sapiens (human) ]

Gene ID: 389333, updated on 25-Jan-2022

Summary

Official Symbol
PROB1provided by HGNC
Official Full Name
proline rich basic protein 1provided by HGNC
Primary source
HGNC:HGNC:41906
See related
Ensembl:ENSG00000228672 AllianceGenome:HGNC:41906
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C5orf65
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See PROB1 in Genome Data Viewer
Location:
5q31.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (139390592..139395104, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (138726281..138730793, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene poly(A) binding protein interacting protein 2 Neighboring gene solute carrier family 23 member 1 Neighboring gene Sharpr-MPRA regulatory region 996 Neighboring gene marginal zone B and B1 cell specific protein Neighboring gene spermatogenesis associated 24 Neighboring gene DnaJ heat shock protein family (Hsp40) member C18

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
proline-rich basic protein 1
Names
weakly similar to basic proline-rich protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161546.2NP_001155018.1  proline-rich basic protein 1

    See identical proteins and their annotated locations for NP_001155018.1

    Status: VALIDATED

    Source sequence(s)
    AC135457, AK316483, AW576390
    Consensus CDS
    CCDS54909.1
    UniProtKB/Swiss-Prot
    E7EW31
    Related
    ENSP00000416033.2, ENST00000434752.4
    Conserved Domains (1) summary
    pfam15232
    Location:874941
    DUF4585; Domain of unknown function (DUF4585)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    139390592..139395104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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