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OR6B2 olfactory receptor family 6 subfamily B member 2 [ Homo sapiens (human) ]

Gene ID: 389090, updated on 22-Sep-2022


Official Symbol
OR6B2provided by HGNC
Official Full Name
olfactory receptor family 6 subfamily B member 2provided by HGNC
Primary source
See related
Ensembl:ENSG00000182083 AllianceGenome:HGNC:15041
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2-1; OR6B2P
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

See OR6B2 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (240029491..240030429, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (240522204..240523142, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (240968908..240969846, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC150935 Neighboring gene NADH:ubiquinone oxidoreductase subunit A10 Neighboring gene microRNA 4786 Neighboring gene olfactory receptor family 6 subfamily B member 3 Neighboring gene olfactory receptor family 9 subfamily S member 24 pseudogene

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


EBI GWAS Catalog

Identification of regions associated with variation in sensitivity to food-related odors in the human genome.
EBI GWAS Catalog

General gene information


Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
located_in plasma membrane IDA
Inferred from Direct Assay
more info

General protein information

Preferred Names
olfactory receptor 6B2
olfactory receptor OR2-1
olfactory receptor, family 6, subfamily B, member 2 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005853.1NP_001005853.1  olfactory receptor 6B2

    See identical proteins and their annotated locations for NP_001005853.1

    Status: VALIDATED

    Source sequence(s)
    Consensus CDS
    Q6IFH4, Q8NGW0
    ENSP00000322435.5, ENST00000319423.5
    Conserved Domains (1) summary
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    240029491..240030429 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060926.1 Alternate T2T-CHM13v2.0

    240522204..240523142 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001001962.1: Suppressed sequence

    NM_001001962.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.