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SPDYE4 speedy/RINGO cell cycle regulator family member E4 [ Homo sapiens (human) ]

Gene ID: 388333, updated on 5-Mar-2024

Summary

Official Symbol
SPDYE4provided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member E4provided by HGNC
Primary source
HGNC:HGNC:35463
See related
Ensembl:ENSG00000183318 MIM:617628; AllianceGenome:HGNC:35463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein kinase binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 1.5) See more
Orthologs
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Genomic context

See SPDYE4 in Genome Data Viewer
Location:
17p13.1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (8747532..8758546, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (8653744..8664766, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (8650850..8661864, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371525 Neighboring gene uncharacterized LOC105371526 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8642150-8642650 Neighboring gene coiled-coil domain containing 42 Neighboring gene uncharacterized LOC105371529 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11700 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11701 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8186 Neighboring gene uncharacterized LOC105371530 Neighboring gene uncharacterized LOC124903918 Neighboring gene major facilitator superfamily domain containing 6 like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
speedy protein E4
Names
putative Speedy protein E4
speedy homolog E4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128076.3NP_001121548.1  speedy protein E4

    See identical proteins and their annotated locations for NP_001121548.1

    Status: VALIDATED

    Source sequence(s)
    AW303450, BC146949
    Consensus CDS
    CCDS45609.1
    UniProtKB/Swiss-Prot
    A6NLX3, B2RUZ6
    Related
    ENSP00000510287.1, ENST00000688021.1
    Conserved Domains (1) summary
    pfam11357
    Location:104233
    Spy1; Cell cycle regulatory protein
  2. NM_001394956.1NP_001381885.1  speedy protein E4

    Status: VALIDATED

    Source sequence(s)
    AC009451
    Consensus CDS
    CCDS45609.1
    UniProtKB/Swiss-Prot
    A6NLX3, B2RUZ6
    Related
    ENSP00000509506.1, ENST00000689094.1
    Conserved Domains (1) summary
    pfam11357
    Location:104233
    Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    8747532..8758546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    8653744..8664766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)