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TMEM233 transmembrane protein 233 [ Homo sapiens (human) ]

Gene ID: 387890, updated on 23-Nov-2021

Summary

Official Symbol
TMEM233provided by HGNC
Official Full Name
transmembrane protein 233provided by HGNC
Primary source
HGNC:HGNC:37219
See related
Ensembl:ENSG00000224982 MIM:618296
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DSPB2; IFITMD2
Expression
Biased expression in thyroid (RPKM 3.9), brain (RPKM 1.9) and 1 other tissue See more
Orthologs
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Genomic context

See TMEM233 in Genome Data Viewer
Location:
12q24.23
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (119592123..119654455)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (120031579..120080880)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 934 Neighboring gene coiled-coil domain containing 60 Neighboring gene uncharacterized LOC105370027 Neighboring gene Sharpr-MPRA regulatory region 763 Neighboring gene RN7SK pseudogene 197 Neighboring gene GATA motif-containing MPRA enhancer 88 Neighboring gene protein kinase AMP-activated non-catalytic subunit beta 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transmembrane protein 233
Names
dispanin subfamily B member 2
interferon induced transmembrane protein domain containing 2
interferon-induced transmembrane domain-containing protein D2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136534.3NP_001130006.1  transmembrane protein 233

    See identical proteins and their annotated locations for NP_001130006.1

    Status: VALIDATED

    Source sequence(s)
    AA476740, AC002563, DC315309, GD264605
    Consensus CDS
    CCDS44995.1
    UniProtKB/Swiss-Prot
    B4DJY2
    Related
    ENSP00000403130.1, ENST00000426426.3
    Conserved Domains (1) summary
    pfam04505
    Location:3388
    CD225; Interferon-induced transmembrane protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    119592123..119654455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005253880.3XP_005253937.1  transmembrane protein 233 isoform X1

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
  2. XM_011538330.2XP_011536632.1  transmembrane protein 233 isoform X3

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
  3. XM_011538329.2XP_011536631.1  transmembrane protein 233 isoform X2

    See identical proteins and their annotated locations for XP_011536631.1

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
  4. XM_011538328.3XP_011536630.1  transmembrane protein 233 isoform X2

    See identical proteins and their annotated locations for XP_011536630.1

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
  5. XM_005253881.3XP_005253938.1  transmembrane protein 233 isoform X2

    See identical proteins and their annotated locations for XP_005253938.1

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
  6. XM_011538331.3XP_011536633.1  transmembrane protein 233 isoform X4

    Conserved Domains (1) summary
    pfam04505
    Location:2988
    CD225; Interferon-induced transmembrane protein
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