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VSTM5 V-set and transmembrane domain containing 5 [ Homo sapiens (human) ]

Gene ID: 387804, updated on 5-Jan-2022

Summary

Official Symbol
VSTM5provided by HGNC
Official Full Name
V-set and transmembrane domain containing 5provided by HGNC
Primary source
HGNC:HGNC:34443
See related
Ensembl:ENSG00000214376
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C11orf90
Summary
Predicted to be involved in filopodium assembly; positive regulation of excitatory synapse assembly; and protein homooligomerization. Predicted to act upstream of or within ventral spinal cord development. Predicted to be located in axon; dendrite; and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in placenta (RPKM 1.5), stomach (RPKM 0.6) and 9 other tissues See more
Orthologs
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Genomic context

See VSTM5 in Genome Data Viewer
Location:
11q21
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (93817315..93850653, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (93551398..93583784, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene chromosome 11 open reading frame 54 Neighboring gene Sharpr-MPRA regulatory region 5970 Neighboring gene mediator complex subunit 17 Neighboring gene uncharacterized LOC101060084 Neighboring gene hypoxanthine phosphoribosyltransferase 1 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in filopodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in filopodium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of excitatory synapse assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of excitatory synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein homooligomerization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in ventral spinal cord development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
V-set and transmembrane domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144871.2NP_001138343.1  V-set and transmembrane domain-containing protein 5 precursor

    See identical proteins and their annotated locations for NP_001138343.1

    Status: VALIDATED

    Source sequence(s)
    AP001894
    Consensus CDS
    CCDS44709.1
    UniProtKB/Swiss-Prot
    A8MXK1
    Related
    ENSP00000386607.1, ENST00000409977.2
    Conserved Domains (2) summary
    smart00410
    Location:42138
    IG_like; Immunoglobulin like
    cl11960
    Location:44138
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    93817315..93850653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001747865.1 RNA Sequence

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