U.S. flag

An official website of the United States government


Send to:

Choose Destination

Mirlet7i microRNA let7i [ Mus musculus (house mouse) ]

Gene ID: 387251, updated on 8-Feb-2024


Official Symbol
Mirlet7iprovided by MGI
Official Full Name
microRNA let7iprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000065406 miRBase:MI0000138; AllianceGenome:MGI:2676802
Gene type
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
let-7i; Mirnlet7i; mmu-let-7i
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Try the new Gene table
Try the new Transcript table

Genomic context

See Mirlet7i in Genome Data Viewer
10 D2; 10 72.1 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (122821545..122821629, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (122985640..122985724, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1H (PP2C domain containing) Neighboring gene predicted gene, 51817 Neighboring gene STARR-seq mESC enhancer starr_28140 Neighboring gene predicted gene, 51818 Neighboring gene STARR-positive B cell enhancer ABC_E8375 Neighboring gene STARR-positive B cell enhancer ABC_E5196 Neighboring gene STARR-positive B cell enhancer ABC_E9356 Neighboring gene STARR-positive B cell enhancer ABC_E10651 Neighboring gene MON2 homolog, regulator of endosome to Golgi trafficking Neighboring gene STARR-positive B cell enhancer ABC_E6936 Neighboring gene ubiquitin specific peptidase 15 Neighboring gene STARR-positive B cell enhancer ABC_E9134 Neighboring gene STARR-positive B cell enhancer ABC_E11464 Neighboring gene predicted gene 4129

Genomic regions, transcripts, and products


GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_029527.1 RNA Sequence


    Source sequence(s)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000076.7 Reference GRCm39 C57BL/6J

    122821545..122821629 complement
    GenBank, FASTA, Sequence Viewer (Graphics)