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Sbk3 SH3 domain binding kinase family, member 3 [ Mus musculus (house mouse) ]

Gene ID: 381835, updated on 11-Apr-2024

Summary

Official Symbol
Sbk3provided by MGI
Official Full Name
SH3 domain binding kinase family, member 3provided by MGI
Primary source
MGI:MGI:2685924
See related
Ensembl:ENSMUSG00000085272 AllianceGenome:MGI:2685924
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1078; Sgk110
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to act upstream of or within phosphorylation. Orthologous to human SBK3 (SH3 domain binding kinase family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in heart adult (RPKM 17.5) and lung adult (RPKM 2.3) See more
Orthologs
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Genomic context

See Sbk3 in Genome Data Viewer
Location:
7 A1; 7 2.87 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4968246..4995756, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4965247..4981041, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene scavenger receptor cysteine rich family, 5 domains Neighboring gene STARR-positive B cell enhancer ABC_E6508 Neighboring gene SH3-binding domain kinase family, member 2 Neighboring gene zinc finger protein 579 Neighboring gene predicted gene, 53351

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
uncharacterized serine/threonine-protein kinase SBK3
Names
SH3-binding domain kinase family member 3
sugen kinase 110
NP_001186970.1
XP_006540196.1
XP_006540198.1
XP_030098575.1
XP_036009088.1
XP_036009089.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001200041.1NP_001186970.1  uncharacterized serine/threonine-protein kinase SBK3

    See identical proteins and their annotated locations for NP_001186970.1

    Status: VALIDATED

    Source sequence(s)
    AC157563, AK138915
    Consensus CDS
    CCDS57475.1
    UniProtKB/Swiss-Prot
    P0C5K0
    Related
    ENSMUSP00000122507.2, ENSMUST00000144863.8
    Conserved Domains (1) summary
    cl21453
    Location:30289
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    4968246..4995756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153196.1XP_036009089.1  uncharacterized serine/threonine-protein kinase SBK3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:30289
    PKc_like; Protein Kinases, catalytic domain
  2. XM_036153195.1XP_036009088.1  uncharacterized serine/threonine-protein kinase SBK3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:30289
    PKc_like; Protein Kinases, catalytic domain
  3. XM_030242715.1XP_030098575.1  uncharacterized serine/threonine-protein kinase SBK3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:30289
    PKc_like; Protein Kinases, catalytic domain
  4. XM_006540135.3XP_006540198.1  uncharacterized serine/threonine-protein kinase SBK3 isoform X2

    See identical proteins and their annotated locations for XP_006540198.1

    UniProtKB/Swiss-Prot
    P0C5K0
    Conserved Domains (1) summary
    cl21453
    Location:30289
    PKc_like; Protein Kinases, catalytic domain
  5. XM_006540133.5XP_006540196.1  uncharacterized serine/threonine-protein kinase SBK3 isoform X1

    See identical proteins and their annotated locations for XP_006540196.1

    UniProtKB/Swiss-Prot
    D3Z5J0, E9QLM1, P0C5K0
    Related
    ENSMUSP00000120654.2, ENSMUST00000133272.2
    Conserved Domains (1) summary
    cl21453
    Location:49308
    PKc_like; Protein Kinases, catalytic domain