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LRRC10 leucine rich repeat containing 10 [ Homo sapiens (human) ]

Gene ID: 376132, updated on 23-Nov-2021

Summary

Official Symbol
LRRC10provided by HGNC
Official Full Name
leucine rich repeat containing 10provided by HGNC
Primary source
HGNC:HGNC:20264
See related
Ensembl:ENSG00000198812 MIM:610846
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HRLRRP; LRRC10A
Orthologs
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Genomic context

See LRRC10 in Genome Data Viewer
Location:
12q15
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (69608564..69610907, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (70002344..70004687, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene microRNA 3913-1 Neighboring gene microRNA 3913-2 Neighboring gene chaperonin containing TCP1 subunit 2 Neighboring gene uncharacterized LOC105369823 Neighboring gene bestrophin 3 Neighboring gene uncharacterized LOC101928002 Neighboring gene RAB3A interacting protein

Genomic regions, transcripts, and products

Bibliography

Phenotypes

Associated conditions

Description Tests
Many sequence variants affecting diversity of adult human height.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC125812

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cardiac muscle cell development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in sarcomere IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
leucine-rich repeat-containing protein 10
Names
heart-restricted leucine-rich repeat protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201550.4NP_963844.2  leucine-rich repeat-containing protein 10

    See identical proteins and their annotated locations for NP_963844.2

    Status: VALIDATED

    Source sequence(s)
    AC018921, BC090881
    Consensus CDS
    CCDS31856.1
    UniProtKB/Swiss-Prot
    Q5BKY1
    Related
    ENSP00000355166.3, ENST00000361484.5
    Conserved Domains (2) summary
    COG4886
    Location:33235
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:5476
    LRR_RI; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    69608564..69610907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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