Ugt49B1 UDP-glycosyltransferase family 49 member B1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ugt49B1provided by FlyBase
Official Full Name: UDP-glycosyltransferase family 49 member B1provided by FlyBase
Primary source: FLYBASE:FBgn0027073
Locus tag: Dmel_CG4302
See related: AllianceGenome:FB:FBgn0027073
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BEST:GH09393; CG4302; Dmel\CG4302; GH09393; UGT49B1
Summary: Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (21212880..21214972, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (17100385..17102477, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables UDP-glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables UDP-glycosyltransferase activity	ISM Inferred from Sequence Model more info	PubMed
enables UDP-glycosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in glycosylation	ISM Inferred from Sequence Model more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
is_active_in endoplasmic reticulum membrane	ISM Inferred from Sequence Model more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain