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ATG44 mitofissin [ Saccharomyces cerevisiae S288C ]

Gene ID: 3628034, updated on 18-Sep-2024

Summary

Official Symbol
ATG44
Official Full Name
mitofissin
Primary source
SGD:S000028511
Locus tag
YIL156W-B
See related
AllianceGenome:SGD:S000028511; FungiDB:YIL156W-B; VEuPathDB:YIL156W-B
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MCO8; MDI1
Summary
Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See ATG44 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
2
Sequence:
Chromosome: IX; NC_001141.2 (47690..47973)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Aim20p Neighboring gene Coa1p Neighboring gene ubiquitin-specific protease UBP7 Neighboring gene glycerol-3-phosphate dehydrogenase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables lipid binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial fission IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mitofissin
NP_001027534.1
  • Mitochondrial fission factor (mitofissin) essential for mitophagy; directly binds to lipid membranes and brings about lipid membrane fragility to facilitate membrane fission; S. pombe homolog complements null mutant

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    47690..47973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184521.1NP_001027534.1  TPA: mitofissin [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_001027534.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVD0, Q2V2P4
    UniProtKB/TrEMBL
    B3LU04, C8ZAV7, G2WFZ5, N1P259
    Conserved Domains (1) summary
    pfam08520
    Location:472
    DUF1748; Fungal protein of unknown function (DUF1748)