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IGLC2 immunoglobulin lambda constant 2 [ Homo sapiens (human) ]

Gene ID: 3538, updated on 8-Dec-2022

Summary

Official Symbol
IGLC2provided by HGNC
Official Full Name
immunoglobulin lambda constant 2provided by HGNC
Primary source
HGNC:HGNC:5856
See related
Ensembl:ENSG00000211677 IMGT/GENE-DB:IGLC2; AllianceGenome:HGNC:5856
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGLC
Summary
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See IGLC2 in Genome Data Viewer
Location:
22q11.22
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (22900976..22901295)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (23323885..23324204)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23243156..23243475)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda locus Neighboring gene immunoglobulin lambda like polypeptide 5 Neighboring gene immunoglobulin lambda constant 1 Neighboring gene immunoglobulin lambda joining 2 Neighboring gene immunoglobulin lambda joining 3 Neighboring gene immunoglobulin lambda constant 3 (Kern-Oz+ marker)

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • C2 segment
  • Ig light-chain, partial Ke-Oz- polypeptide, C-term
  • immunoglobulin lambda constant 2 (Kern-Oz- marker)
  • immunoglobulin lambda constant region 2 (Kern- Oz- marker)

Clone Names

  • MGC20392, MGC45681

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_000002.1 

    Range
    867140..867459
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    22900976..22901295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    23323885..23324204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)