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Tc00.1047053510167.10 phosphatidylinositol 3-kinase 2, putative [ Trypanosoma cruzi ]

Gene ID: 3535692, updated on 23-Nov-2023

Summary

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Gene symbol
Tc00.1047053510167.10
Gene description
phosphatidylinositol 3-kinase 2, putative
Locus tag
Tc00.1047053510167.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Trypanosoma cruzi (strain: CL Brener)
Lineage
Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum
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Genomic context

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Location:
chromosome: Unknown
Exon count:
1

NW_001849436.1Genomic Context describing neighboring genes Neighboring gene SNF2 DNA repair protein, putative Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene exosome complex exonuclease, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_001849436.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020725
  2. Comparative genomics of trypanosomatid parasitic protozoa. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020724

GeneRIFs: Gene References Into Functions

General gene information

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Homology

  • heterozygous, Esmeraldo-like haplotype
    allele of Tc00.1047053508859.90

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase 2, putative
XP_805828.1
  • heterozygous, Esmeraldo-like haplotype
    allele of Tc00.1047053508859.90

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_001849436.1 Reference assembly

    Range
    115465..118632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_800735.1 → XP_805828.1  phosphatidylinositol 3-kinase 2, putative [Trypanosoma cruzi]

    See identical proteins and their annotated locations for XP_805828.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2V2WA30, Q4CUM7, V5AXQ0
    Conserved Domains (4) summary
    cd08380
    Location:292 → 499
    C2_PI3K_like; C2 domain present in phosphatidylinositol 3-kinases (PI3Ks)
    cd00891
    Location:707 → 1038
    PI3Kc; Catalytic domain of Phosphoinositide 3-kinase
    cl00271
    Location:535 → 702
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:177 → 248
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

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