Rnu11 U11 small nuclear RNA [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rnu11provided by MGI
Official Full Name: U11 small nuclear RNAprovided by MGI
Primary source: MGI:MGI:2148804
See related: AllianceGenome:MGI:2148804
Gene type: snRNA
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mirn801; mir-801; MBII-407; mmu-mir-801
Summary: Acts upstream of or within RNA splicing. Is expressed in several structures, including branchial arch; limb; limb primordium; neural retina; and somite. Orthologous to human RNU11 (RNA, U11 small nuclear). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 4 D2.3; 4 65.08 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (131997390..131997497, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (132270079..132270186, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

U11snRNA robustly activated the TLR7 pathway in vitro and induced arthritis disease in vivo. U11snRNA induced type I IFN gene expression in splenocytes.
Title: Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (3) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.