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ANKRD37 ankyrin repeat domain 37 [ Homo sapiens (human) ]

Gene ID: 353322, updated on 23-Nov-2021

Summary

Official Symbol
ANKRD37provided by HGNC
Official Full Name
ankyrin repeat domain 37provided by HGNC
Primary source
HGNC:HGNC:29593
See related
Ensembl:ENSG00000186352 MIM:619021
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Lrp2bp
Expression
Ubiquitous expression in esophagus (RPKM 19.3), prostate (RPKM 17.2) and 25 other tissues See more
Orthologs
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Genomic context

See ANKRD37 in Genome Data Viewer
Location:
4q35.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (185396841..185400243)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (186317995..186321395)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene sorting nexin 25 Neighboring gene Sharpr-MPRA regulatory region 12245 Neighboring gene uncharacterized LOC107986206 Neighboring gene LRP2 binding protein Neighboring gene chromosome 4 open reading frame 47 Neighboring gene UFM1 specific peptidase 2 Neighboring gene coiled-coil domain containing 110 Neighboring gene uncharacterized LOC105377590

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111507

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 37
Names
low density lipoprotein receptor-related protein binding protein
low-density lipoprotein receptor-related protein 2-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181726.4NP_859077.1  ankyrin repeat domain-containing protein 37

    See identical proteins and their annotated locations for NP_859077.1

    Status: VALIDATED

    Source sequence(s)
    AY296056, BC088376
    Consensus CDS
    CCDS3841.1
    UniProtKB/Swiss-Prot
    Q7Z713
    Related
    ENSP00000335147.4, ENST00000335174.6
    Conserved Domains (3) summary
    cd00204
    Location:10116
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:66116
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:3261
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    185396841..185400243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008176.1XP_016863665.1  ankyrin repeat domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    B4E066
    Conserved Domains (3) summary
    cd00204
    Location:10116
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:66116
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:3261
    ANK; ANK repeat [structural motif]
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