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LCE1E late cornified envelope 1E [ Homo sapiens (human) ]

Gene ID: 353135, updated on 21-Mar-2023

Summary

Official Symbol
LCE1Eprovided by HGNC
Official Full Name
late cornified envelope 1Eprovided by HGNC
Primary source
HGNC:HGNC:29466
See related
Ensembl:ENSG00000186226 MIM:612607; AllianceGenome:HGNC:29466
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP5
Summary
Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward skin (RPKM 20.8) See more
Orthologs
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Genomic context

See LCE1E in Genome Data Viewer
Location:
1q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152786257..152788426)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151922800..151924970)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152758733..152760902)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene keratinocyte proline rich protein Neighboring gene late cornified envelope 1F Neighboring gene late cornified envelope 1D Neighboring gene late cornified envelope 1C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in keratinization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
late cornified envelope protein 1E
Names
late envelope protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178353.2NP_848130.1  late cornified envelope protein 1E

    See identical proteins and their annotated locations for NP_848130.1

    Status: VALIDATED

    Source sequence(s)
    AL353779, BC038391
    Consensus CDS
    CCDS1024.1
    UniProtKB/Swiss-Prot
    D3DV30, Q5T753
    Related
    ENSP00000357759.3, ENST00000368770.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152786257..152788426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151922800..151924970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)