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LCE1B late cornified envelope 1B [ Homo sapiens (human) ]

Gene ID: 353132, updated on 13-May-2022

Summary

Official Symbol
LCE1Bprovided by HGNC
Official Full Name
late cornified envelope 1Bprovided by HGNC
Primary source
HGNC:HGNC:16611
See related
Ensembl:ENSG00000196734 MIM:612604; AllianceGenome:HGNC:16611
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP2; SPRL2A
Summary
Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See LCE1B in Genome Data Viewer
Location:
1q21.3
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152811971..152813108)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151948528..151949665)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152784447..152785584)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope 1D Neighboring gene late cornified envelope 1C Neighboring gene late cornified envelope 1A Neighboring gene late cornified envelope 6A

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in keratinization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
late cornified envelope protein 1B
Names
late envelope protein 2
small proline rich-like (epidermal differentiation complex) 2A
small proline-rich-like epidermal differentiation complex protein 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178349.2NP_848126.1  late cornified envelope protein 1B

    See identical proteins and their annotated locations for NP_848126.1

    Status: VALIDATED

    Source sequence(s)
    BC031811
    Consensus CDS
    CCDS1027.1
    UniProtKB/Swiss-Prot
    Q5T7P3
    Related
    ENSP00000353203.3, ENST00000360090.4

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152811971..152813108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151948528..151949665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)