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MPC1L mitochondrial pyruvate carrier 1 like [ Homo sapiens (human) ]

Gene ID: 347411, updated on 22-Sep-2022

Summary

Official Symbol
MPC1Lprovided by HGNC
Official Full Name
mitochondrial pyruvate carrier 1 likeprovided by HGNC
Primary source
HGNC:HGNC:44205
See related
Ensembl:ENSG00000238205 AllianceGenome:HGNC:44205
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SLC54A3
Summary
Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See MPC1L in Genome Data Viewer
Location:
Xp11.4
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (40623428..40624136)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (40024973..40025681)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (40482680..40483388)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene RNA, U7 small nuclear 164 pseudogene Neighboring gene ATPase H+ transporting accessory protein 2 Neighboring gene chromosome X open reading frame 38 Neighboring gene mediator complex subunit 14 Neighboring gene MED14 opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables pyruvate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial pyruvate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
mitochondrial pyruvate carrier 1-like protein
Names
brain protein 44-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195522.3NP_001182451.1  mitochondrial pyruvate carrier 1-like protein

    See identical proteins and their annotated locations for NP_001182451.1

    Status: VALIDATED

    Source sequence(s)
    AC092473
    Consensus CDS
    CCDS83466.1
    UniProtKB/Swiss-Prot
    P0DKB6
    Related
    ENSP00000489748.1, ENST00000423387.4
    Conserved Domains (1) summary
    pfam03650
    Location:2699
    MPC; uncharacterized protein family (UPF0041)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    40623428..40624136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    40024973..40025681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)