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IGFBPL1 insulin like growth factor binding protein like 1 [ Homo sapiens (human) ]

Gene ID: 347252, updated on 1-Jun-2020

Summary

Official Symbol
IGFBPL1provided by HGNC
Official Full Name
insulin like growth factor binding protein like 1provided by HGNC
Primary source
HGNC:HGNC:20081
See related
Ensembl:ENSG00000137142 MIM:610413
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGFBPRP4; IGFBP-RP4; bA113O24.1
Expression
Biased expression in thyroid (RPKM 9.9), brain (RPKM 1.8) and 3 other tissues See more
Orthologs

Genomic context

See IGFBPL1 in Genome Data Viewer
Location:
9p13.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (38406528..38424454, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (38406525..38424444, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107987065 Neighboring gene uncharacterized LOC105376040 Neighboring gene aldehyde dehydrogenase 1 family member B1 Neighboring gene uncharacterized LOC105376041 Neighboring gene VISTA enhancer hs1390 Neighboring gene armadillo repeat containing 8 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
insulin-like growth factor binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cellular response to tumor cell IEP
Inferred from Expression Pattern
more info
PubMed 
regulation of cell growth IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
insulin-like growth factor-binding protein-like 1
Names
IGFBP-related protein 10
insulin-like growth factor binding protein related protein 4
insulin-like growth factor-binding-related protein 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007563.3NP_001007564.1  insulin-like growth factor-binding protein-like 1 precursor

    See identical proteins and their annotated locations for NP_001007564.1

    Status: VALIDATED

    Source sequence(s)
    AL135785
    Consensus CDS
    CCDS35017.1
    UniProtKB/Swiss-Prot
    Q8WX77
    Related
    ENSP00000366923.1, ENST00000377694.2
    Conserved Domains (2) summary
    smart00280
    Location:114151
    KAZAL; Kazal type serine protease inhibitors
    cl28434
    Location:169260
    I-set; Immunoglobulin I-set domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    38406528..38424454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017014699.1XP_016870188.1  insulin-like growth factor-binding protein-like 1 isoform X1

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