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TCEAL5 transcription elongation factor A like 5 [ Homo sapiens (human) ]

Gene ID: 340543, updated on 8-Dec-2022

Summary

Official Symbol
TCEAL5provided by HGNC
Official Full Name
transcription elongation factor A like 5provided by HGNC
Primary source
HGNC:HGNC:22282
See related
Ensembl:ENSG00000204065 AllianceGenome:HGNC:22282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WEX4
Summary
This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked like family) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongation factor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirely in the terminal exon. [provided by RefSeq, Sep 2011]
Expression
Biased expression in testis (RPKM 33.5), brain (RPKM 32.2) and 3 other tissues See more
Orthologs
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Genomic context

See TCEAL5 in Genome Data Viewer
Location:
Xq22.1
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (103273691..103276750, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (101720668..101723727, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (102528619..102531678, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene guanosine monophosphate reductase pseudogene Neighboring gene transcription elongation factor A like 8 Neighboring gene brain expressed X-linked 2 Neighboring gene transcription elongation factor A like 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
transcription elongation factor A protein-like 5
Names
TCEA-like protein 5
transcription elongation factor A (SII)-like 5
transcription elongation factor S-II protein-like 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016591.1 RefSeqGene

    Range
    5120..8179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001012979.3NP_001012997.1  transcription elongation factor A protein-like 5

    See identical proteins and their annotated locations for NP_001012997.1

    Status: REVIEWED

    Source sequence(s)
    BC132924, BM725918, Z68694
    Consensus CDS
    CCDS35356.1
    UniProtKB/Swiss-Prot
    A2RUJ4, Q5H9L2
    Related
    ENSP00000361765.1, ENST00000372680.2
    Conserved Domains (2) summary
    pfam04538
    Location:87179
    BEX; Brain expressed X-linked like family
    cl27511
    Location:6166
    Na_Ca_ex; Sodium/calcium exchanger protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    103273691..103276750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    101720668..101723727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)