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gudu gudu [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34014, updated on 18-Sep-2024

Summary

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Official Symbol
guduprovided by FlyBase
Official Full Name
guduprovided by FlyBase
Primary source
FLYBASE:FBgn0031905
Locus tag
Dmel_CG5155
See related
AllianceGenome:FB:FBgn0031905
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5155; Dmel\CG5155; Gudu
Summary
Involved in sperm individualization. Is expressed in adult head; spermatogonium; spermatozoon; and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 23. Orthologous to human ODAD2 (outer dynein arm docking complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
27F3-27F3; 2-26 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7388508..7390902)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7388508..7390902)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene neither inactivation nor afterpotential C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila. Cheng W, et al. Gene, 2013 Dec 1. PMID 24055424, Free PMC Article
  2. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
  3. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  4. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sperm individualization IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
gudu
Names
CG5155-PA
gudu-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7388508..7390902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135267.3 → NP_609111.1  gudu [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609111.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q6NNW8, Q9VM21
    Related
    FBpp0079066
    Conserved Domains (3) summary
    smart00185
    Location:614 → 652
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:105 → 134
    ARM; armadillo repeat [structural motif]
    cl25709
    Location:214 → 557
    Arm_3; Atypical Arm repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VM21.1 Q9VM21

Gene LinkOut

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