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TFAP2E transcription factor AP-2 epsilon [ Homo sapiens (human) ]

Gene ID: 339488, updated on 18-Aug-2020

Summary

Official Symbol
TFAP2Eprovided by HGNC
Official Full Name
transcription factor AP-2 epsilonprovided by HGNC
Primary source
HGNC:HGNC:30774
See related
Ensembl:ENSG00000116819 MIM:614428
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AP2E
Expression
Broad expression in skin (RPKM 1.5), lymph node (RPKM 1.1) and 22 other tissues See more
Orthologs

Genomic context

See TFAP2E in Genome Data Viewer
Location:
1p34.3
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (35568739..35595591)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (36038971..36060929)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene KIAA0319 like Neighboring gene zinc finger protein 485 pseudogene Neighboring gene TFAP2E antisense RNA 1 Neighboring gene neurochondrin Neighboring gene proteasome 20S subunit beta 2 Neighboring gene uncharacterized LOC105378646

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Clone Names

  • MGC49007

Gene Ontology Provided by GOA

Process Evidence Code Pubs
anatomical structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription factor AP-2-epsilon
Names
AP2-epsilon
activating enhancer-binding protein 2-epsilon
adaptor-related protein complex 2, epsilon subunit
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178548.4NP_848643.2  transcription factor AP-2-epsilon

    See identical proteins and their annotated locations for NP_848643.2

    Status: VALIDATED

    Source sequence(s)
    AC004865, AL157951
    Consensus CDS
    CCDS393.2
    UniProtKB/Swiss-Prot
    Q6VUC0
    Related
    ENSP00000362332.3, ENST00000373235.4
    Conserved Domains (1) summary
    pfam03299
    Location:216414
    TF_AP-2; Transcription factor AP-2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    35568739..35595591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001139.2XP_016856628.1  transcription factor AP-2-epsilon isoform X1

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