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CENATAC centrosomal AT-AC splicing factor [ Homo sapiens (human) ]

Gene ID: 338657, updated on 8-Aug-2021

Summary

Official Symbol
CENATACprovided by HGNC
Official Full Name
centrosomal AT-AC splicing factorprovided by HGNC
Primary source
HGNC:HGNC:30460
See related
Ensembl:ENSG00000186166
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCDC84; DLNB14
Summary
This gene encodes a protein thought to contain a coiled coil motif. No function has been determined for the encoded protein. A pseudogene of this gene is located on chromosome 20. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Expression
Ubiquitous expression in skin (RPKM 3.1), spleen (RPKM 2.7) and 25 other tissues See more
Orthologs
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Genomic context

See CENATAC in Genome Data Viewer
Location:
11q23.3
Exon count:
12
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (118998138..119015793)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (118868848..118886503)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene forkhead box R1 Neighboring gene Sharpr-MPRA regulatory region 14267 Neighboring gene CENATAC divergent transcript Neighboring gene ribosomal protein L23a pseudogene 64 Neighboring gene ribosomal protein S25 Neighboring gene trafficking protein particle complex subunit 4 Neighboring gene solute carrier family 37 member 4 Neighboring gene hypoxia up-regulated 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
centrosomal AT-AC splicing factor
Names
coiled-coil domain containing 84
coiled-coil domain-containing protein 84

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050577.1 RefSeqGene

    Range
    8786..26441
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_198489.3NP_940891.1  centrosomal AT-AC splicing factor

    See identical proteins and their annotated locations for NP_940891.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the shortest transcript.
    Source sequence(s)
    AB094093, BU733365, HY073607
    Consensus CDS
    CCDS8405.1
    UniProtKB/Swiss-Prot
    Q86UT8
    Related
    ENSP00000334767.1, ENST00000334418.6
    Conserved Domains (1) summary
    pfam14968
    Location:7322
    CCDC84; Coiled coil protein 84

RNA

  1. NR_104049.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AW014772, BC144209, BU733365, HY073607
  2. NR_104050.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses alternate splice sites in two internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC144210, BU733365, DB565963, HY073607
    Related
    ENST00000532132.5
  3. NR_104051.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site in an internal exon, contains an alternate exon, and lacks an alternate exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC144208, BG251503, BU733365, HY073607
    Related
    ENST00000526463.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    118998138..119015793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646203.1 Reference GRCh38.p13 PATCHES

    Range
    19738..37393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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