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IFNE interferon epsilon [ Homo sapiens (human) ]

Gene ID: 338376, updated on 11-Jun-2021

Summary

Official Symbol
IFNEprovided by HGNC
Official Full Name
interferon epsilonprovided by HGNC
Primary source
HGNC:HGNC:18163
See related
Ensembl:ENSG00000184995 MIM:615223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IFN-E; IFNE1; IFNT1; INFE1; PRO655
Orthologs
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Genomic context

See IFNE in Genome Data Viewer
Location:
9p21.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (21480839..21482313, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (21480838..21482312, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene interferon alpha 1 Neighboring gene MIR31 host gene Neighboring gene interferon omega 1 pseudogene 19 Neighboring gene microRNA 31 Neighboring gene H3 histone pseudogene 30

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
THOC5: a novel gene involved in HDL-cholesterol metabolism.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119018, MGC119020

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables type I interferon receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in B cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in B cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in T cell activation involved in immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in adaptive immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cytokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to bacterium ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in defense response to virus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in humoral immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in natural killer cell activation involved in immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to exogenous dsRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
interferon epsilon
Names
IFN-epsilon
interferon epsilon 1
interferon tau-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176891.5NP_795372.1  interferon epsilon precursor

    See identical proteins and their annotated locations for NP_795372.1

    Status: VALIDATED

    Source sequence(s)
    AL353732
    Consensus CDS
    CCDS34997.1
    UniProtKB/Swiss-Prot
    Q86WN2
    Related
    ENSP00000418018.2, ENST00000448696.4
    Conserved Domains (1) summary
    pfam00143
    Location:29186
    Interferon; Interferon alpha/beta domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    21480839..21482313 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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