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S100A7A S100 calcium binding protein A7A [ Homo sapiens (human) ]

Gene ID: 338324, updated on 8-Aug-2021

Summary

Official Symbol
S100A7Aprovided by HGNC
Official Full Name
S100 calcium binding protein A7Aprovided by HGNC
Primary source
HGNC:HGNC:21657
See related
Ensembl:ENSG00000184330 MIM:617427
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NICE2; NICE-2; S100A15; S100A7f; S100A7L1
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See S100A7A in Genome Data Viewer
Location:
1q21.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (153416520..153423222)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153388996..153395698)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene lysosomal protein transmembrane 4 beta pseudogene 1 Neighboring gene S100 calcium binding protein A8 Neighboring gene S100 calcium binding protein A15A (pseudogene) Neighboring gene S100 calcium binding protein A7 pseudogene 1 Neighboring gene CRISPRi-validated cis-regulatory element chr1.8681

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein self-association IDA
Inferred from Direct Assay
more info
PubMed 
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein S100-A7A
Names
S100 calcium-binding protein A15
S100 calcium-binding protein A7-like 1
koebnerisin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176823.4NP_789793.1  protein S100-A7A

    See identical proteins and their annotated locations for NP_789793.1

    Status: VALIDATED

    Source sequence(s)
    AJ243672, AL591704, AY189118
    Consensus CDS
    CCDS30872.1
    UniProtKB/Swiss-Prot
    Q86SG5
    Related
    ENSP00000357718.3, ENST00000368729.9
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    153416520..153423222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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