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CG15739 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32146, updated on 26-Apr-2024

Summary

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Official Symbol
CG15739provided by FlyBase
Primary source
FLYBASE:FBgn0030347
Locus tag
Dmel_CG15739
See related
AllianceGenome:FB:FBgn0030347
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
17945012; Dmel\CG15739; FPPase; Phos15739
Summary
Enables phosphatase activity. Involved in dephosphorylation. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval crystal cell; embryonic/larval fat body; procrystal cell; ring gland; and yolk nucleus. Orthologous to human PGP (phosphoglycolate phosphatase) and PDXP (pyridoxal phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
10F2-10F2; 1-37 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11873319..11875346)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11767352..11769379)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene BLOC-1 related complex subunit 5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Selenoprotein G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An insect farnesyl phosphatase homologous to the N-terminal domain of soluble epoxide hydrolase. Cao L, et al. Biochem Biophys Res Commun, 2009 Feb 27. PMID 19168029, Free PMC Article
  2. Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine. Zhang CH, et al. J Insect Sci, 2019 May 1. PMID 31115476, Free PMC Article
  3. RACK1 modulates polyglutamine-induced neurodegeneration by promoting ERK degradation in Drosophila. Xie J, et al. PLoS Genet, 2021 May. PMID 33983927, Free PMC Article
  4. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region. Organista MF, et al. PLoS Genet, 2015 Aug. PMID 26241320, Free PMC Article
  5. Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. Napoletano F, et al. EMBO J, 2011 Mar 2. PMID 21278706, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15739-PA
CG15739-PB
NP_001259467.1
NP_572760.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11873319..11875346
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132532.4 → NP_572760.1  uncharacterized protein Dmel_CG15739, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572760.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZD4, Q9VYT0
    Related
    FBpp0073413
    Conserved Domains (3) summary
    TIGR01452
    Location:23 → 296
    PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
    pfam13242
    Location:219 → 295
    Hydrolase_like; HAD-hyrolase-like
    pfam13344
    Location:25 → 125
    Hydrolase_6; Haloacid dehalogenase-like hydrolase

  2. NM_001272538.1 → NP_001259467.1  uncharacterized protein Dmel_CG15739, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259467.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZD4, Q9VYT0
    Conserved Domains (3) summary
    TIGR01452
    Location:23 → 296
    PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
    pfam13242
    Location:219 → 295
    Hydrolase_like; HAD-hyrolase-like
    pfam13344
    Location:25 → 125
    Hydrolase_6; Haloacid dehalogenase-like hydrolase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VYT0 Q9VYT0

Gene LinkOut

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