U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

H2ac10 H2A clustered histone 10 [ Mus musculus (house mouse) ]

Gene ID: 319173, updated on 11-Apr-2024

Summary

Official Symbol
H2ac10provided by MGI
Official Full Name
H2A clustered histone 10provided by MGI
Primary source
MGI:MGI:2448309
See related
Ensembl:ENSMUSG00000061991 AllianceGenome:MGI:2448309
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2a-221; Hist1h2af
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See H2ac10 in Genome Data Viewer
Location:
13 A3.1; 13 9.77 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23718045..23718548)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23533875..23534378)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11335 Neighboring gene nuclear encoded tRNA methionine 9 (anticodon CAT) Neighboring gene H4 clustered histone 8 Neighboring gene STARR-positive B cell enhancer ABC_E4057 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23627005-23627306 Neighboring gene H3 clustered histone 8 Neighboring gene STARR-positive B cell enhancer ABC_E4059 Neighboring gene H2B clustered histone 9

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
histone H2A type 1-F
Names
histone 1, H2af
histone H2a (aa 92-128)
histone cluster 1, H2af

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175661.3NP_783592.1  histone H2A type 1-F

    See identical proteins and their annotated locations for NP_783592.1

    Status: REVIEWED

    Source sequence(s)
    AL592149
    Consensus CDS
    CCDS26341.1
    UniProtKB/Swiss-Prot
    Q08AU5, Q8CGP5
    UniProtKB/TrEMBL
    A0AUV1
    Related
    ENSMUSP00000072989.3, ENSMUST00000073261.3
    Conserved Domains (1) summary
    PTZ00017
    Location:1130
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    23718045..23718548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)