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Vha36-3 Vacuolar H[+] ATPase 36kD subunit 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31235, updated on 11-Sep-2024

Summary

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Official Symbol
Vha36-3provided by FlyBase
Official Full Name
Vacuolar H[+] ATPase 36kD subunit 3provided by FlyBase
Primary source
FLYBASE:FBgn0040377
Locus tag
Dmel_CG8310
See related
AllianceGenome:FB:FBgn0040377
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8310; Dmel\CG8310; EG:BACR25B3.4; vha36-3
Summary
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of proton-transporting V-type ATPase complex. Is expressed in adult head. Orthologous to human ATP6V1D (ATPase H+ transporting V1 subunit D). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
3A6-3A6; 1-1 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2579091..2580560, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2473124..2474593, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene terribly reduced optic lobes Neighboring gene mir-4955 stem loop Neighboring gene Pigment-dispersing factor receptor Neighboring gene Arylalkylamine N-acetyltransferase-like 7 Neighboring gene uncharacterized protein Neighboring gene will die slowly

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. Greco TM, et al. Cell Syst, 2022 Apr 20. PMID 35148841, Free PMC Article
  2. Recent origins of sperm genes in Drosophila. Dorus S, et al. Mol Biol Evol, 2008 Oct. PMID 18653731, Free PMC Article
  3. A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior. Lear BC, et al. Neuron, 2005 Oct 20. PMID 16242403
  4. Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Allan AK, et al. Physiol Genomics, 2005 Jul 14. PMID 15855386
  5. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to proton-transporting ATPase activity, rotational mechanism IC
Inferred by Curator
more info
  
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proton transmembrane transport IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of proton-transporting V-type ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proton-transporting V-type ATPase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
vacuolar H[+] ATPase 36kD subunit 3
Names
CG8310-PB
CG8310-PC
Vha36-3-PB
Vha36-3-PC
vacuolar H[+] ATPase subunit 36-3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2579091..2580560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001297899.1 → NP_001284828.1  vacuolar H[+] ATPase 36kD subunit 3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284828.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9I7X1, Q9NEF6
    UniProtKB/TrEMBL
    X2JE14
    Conserved Domains (1) summary
    pfam01813
    Location:17 → 206
    ATP-synt_D; ATP synthase subunit D

  2. NM_130652.4 → NP_570008.1  vacuolar H[+] ATPase 36kD subunit 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570008.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9I7X1, Q9NEF6
    UniProtKB/TrEMBL
    X2JE14
    Related
    FBpp0308493
    Conserved Domains (1) summary
    pfam01813
    Location:17 → 206
    ATP-synt_D; ATP synthase subunit D
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NEF6.1 Q9NEF6
X2JE14 X2JE14

Gene LinkOut

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