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CG11596 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31158, updated on 18-Sep-2024

Summary

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Official Symbol
CG11596provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0023522
Locus tag
Dmel_CG11596
See related
AllianceGenome:FB:FBgn0023522
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11596; EG:39E1.1
Summary
Predicted to enable carnosine N-methyltransferase activity. Predicted to be involved in carnosine metabolic process. Predicted to be active in cytosol and nucleus. Is expressed in organism. Orthologous to human CARNMT1 (carnosine N-methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
2B16-2B16; 1-0.2 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1927683..1930517)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1821716..1824550)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Myb-interacting protein 130 Neighboring gene eukaryotic translation initiation factor 2B subunit epsilon Neighboring gene Oculocerebrorenal syndrome of Lowe Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila MSL complex activates the transcription of target genes. Straub T, et al. Genes Dev, 2005 Oct 1. PMID 16204179, Free PMC Article
  2. Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila. Monzo K, et al. Dev Biol, 2010 Apr 15. PMID 20122915, Free PMC Article
  3. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
  4. Adaptation to Chronic Nutritional Stress Leads to Reduced Dependence on Microbiota in Drosophila melanogaster. Erkosar B, et al. mBio, 2017 Oct 24. PMID 29066546, Free PMC Article
  5. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables amino acid sensor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables carnosine N-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carnosine N-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in carnosine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carnosine metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cellular response to amino acid starvation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to methionine IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11596-PA
CG11596-PB
CG11596-PC
CG11596-PD
CG11596-PE
NP_001259154.1
NP_001259155.1
NP_569963.1
NP_726779.1
NP_726780.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    1927683..1930517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130607.3 → NP_569963.1  uncharacterized protein Dmel_CG11596, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569963.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O46078, Q7KW04, Q9I7X6, Q9W540
    Related
    FBpp0070306
    Conserved Domains (1) summary
    pfam07942
    Location:114 → 379
    N2227; N2227-like protein

  2. NM_166916.2 → NP_726779.1  uncharacterized protein Dmel_CG11596, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726779.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E4NKI7
    Related
    FBpp0070305
    Conserved Domains (1) summary
    pfam07942
    Location:114 → 396
    N2227; N2227-like protein

  3. NM_001272226.1 → NP_001259155.1  uncharacterized protein Dmel_CG11596, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259155.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PGG7
    Conserved Domains (1) summary
    pfam07942
    Location:59 → 341
    N2227; N2227-like protein

  4. NM_166917.2 → NP_726780.1  uncharacterized protein Dmel_CG11596, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726780.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PGG7
    Related
    FBpp0070307
    Conserved Domains (1) summary
    pfam07942
    Location:59 → 341
    N2227; N2227-like protein

  5. NM_001272225.1 → NP_001259154.1  uncharacterized protein Dmel_CG11596, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259154.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PGG7
    Conserved Domains (1) summary
    pfam07942
    Location:59 → 341
    N2227; N2227-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PGG7 M9PGG7
Q9I7X6.1 Q9I7X6

Gene LinkOut

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