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CAB2 phosphopantothenate--cysteine ligase CAB2 [ Sugiyamaella lignohabitans ]

Gene ID: 30037108, updated on 9-Jan-2024

Summary

Gene symbol
CAB2
Gene description
phosphopantothenate--cysteine ligase CAB2
Locus tag
AWJ20_4923
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sugiyamaella lignohabitans (strain: CBS 10342, type-material: culture from holotype of Candida lignohabitans)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Trichomonascaceae; Sugiyamaella
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Genomic context

Location:
chromosome: D
Exon count:
2
Sequence:
Chromosome: D; NC_031673.1 (938658..941835, complement)

Chromosome D - NC_031673.1Genomic Context describing neighboring genes Neighboring gene Exo84p Neighboring gene Tri1p Neighboring gene Pub1p Neighboring gene Ubp1p

General protein information

Preferred Names
phosphopantothenate--cysteine ligase CAB2
XP_018736447.1
  • Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity); GO_component: GO:0005737 - cytoplasm [Evidence IEA,IEA]; GO_component: GO:0005737 - cytoplasm [Evidence IDA] [PMID 14690591]; GO_component: GO:0005634 - nucleus [Evidence IEA,IEA]; GO_component: GO:0005634 - nucleus [Evidence IDA] [PMID 14690591]; GO_function: GO:0016874 - ligase activity [Evidence IEA]; GO_function: GO:0004632 - phosphopantothenate--cysteine ligase activity [Evidence IEA]; GO_function: GO:0004632 - phosphopantothenate--cysteine ligase activity [Evidence ISS] [PMID 11923312]; GO_process: GO:0015937 - coenzyme A biosynthetic process [Evidence IEA,IEA]; GO_process: GO:0015937 - coenzyme A biosynthetic process [Evidence ISS] [PMID 11923312]; GO_process: GO:0015937 - coenzyme A biosynthetic process [Evidence IGI] [PMID 19266201]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_031673.1 Reference assembly

    Range
    938658..941835 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018882028.1XP_018736447.1  phosphopantothenate--cysteine ligase CAB2 [Sugiyamaella lignohabitans]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A161HEY5