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ERG6 sterol 24-C-methyltransferase [ Sugiyamaella lignohabitans ]

Gene ID: 30034052, updated on 9-Jan-2024

Summary

Gene symbol
ERG6
Gene description
sterol 24-C-methyltransferase
Locus tag
AWJ20_2170
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sugiyamaella lignohabitans (strain: CBS 10342, type-material: culture from holotype of Candida lignohabitans)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Trichomonascaceae; Sugiyamaella
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Genomic context

Location:
chromosome: B
Exon count:
1
Sequence:
Chromosome: B; NC_031674.1 (573306..574433)

Chromosome B - NC_031674.1Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene aminophospholipid translocase regulatory protein CDC50 Neighboring gene hexose transporter HXT6 Neighboring gene Agc1p

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sterol 24-C-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in ergosterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
sterol 24-C-methyltransferase
XP_018737047.1
  • Delta(24)-sterol C-methyltransferase; converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to lipid particles, the plasma membrane-associated endoplasmic reticulum, and the mitochondrial outer membrane; GO_component: GO:0005783 - endoplasmic reticulum [Evidence IDA] [PMID 11298754]; GO_component: GO:0005783 - endoplasmic reticulum [Evidence IDA] [PMID 9450962]; GO_component: GO:0005811 - lipid particle [Evidence IDA] [PMID 10515935]; GO_component: GO:0005811 - lipid particle [Evidence IDA] [PMID 24868093]; GO_component: GO:0005741 - mitochondrial outer membrane [Evidence IDA] [PMID 16407407]; GO_component: GO:0005739 - mitochondrion [Evidence IDA] [PMID 14576278]; GO_component: GO:0005739 - mitochondrion [Evidence IDA] [PMID 16823961]; GO_function: GO:0008168 - methyltransferase activity [Evidence IEA,IEA]; GO_function: GO:0003838 - sterol 24-C-methyltransferase activity [Evidence IEA,IEA]; GO_function: GO:0003838 - sterol 24-C-methyltransferase activity [Evidence IDA] [PMID 18563465]; GO_function: GO:0016740 - transferase activity [Evidence IEA]; GO_process: GO:0006696 - ergosterol biosynthetic process [Evidence IMP] [PMID 2677674]; GO_process: GO:0006696 - ergosterol biosynthetic process [Evidence IMP] [PMID 6363386]; GO_process: GO:0006629 - lipid metabolic process [Evidence IEA]; GO_process: GO:0008152 - metabolic process [Evidence IEA]; GO_process: GO:0032259 - methylation [Evidence IEA]; GO_process: GO:0006694 - steroid biosynthetic process [Evidence IEA,IEA]; GO_process: GO:0008202 - steroid metabolic process [Evidence IEA]; GO_process: GO:0016126 - sterol biosynthetic process [Evidence IEA,IEA]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_031674.1 Reference assembly

    Range
    573306..574433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018879099.1XP_018737047.1  sterol 24-C-methyltransferase [Sugiyamaella lignohabitans]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A161HFZ4