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Or4f4a olfactory receptor family 4 subfamily F member 4A [ Rattus norvegicus (Norway rat) ]

Gene ID: 296016, updated on 17-Aug-2024

Summary

Official Symbol
Or4f4aprovided by RGD
Official Full Name
olfactory receptor family 4 subfamily F member 4Aprovided by RGD
Primary source
RGD:1333654
See related
AllianceGenome:RGD:1333654
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Olr763; Or4f4b; Olfr1289; ratchr3-96979662-96980579_ORF
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
3q34
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (118551424..118555594)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (98096906..98101076)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (102701378..102704404)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily F member 5 Neighboring gene olfactory receptor family 4 subfamily K member 42C, pseudogene 1 Neighboring gene olfactory receptor family 4 subfamily K member 42, pseudogene 1 Neighboring gene olfactory receptor 765

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 4F4; olfactory receptor Olr763
Names
olfactory receptor 1289
olfactory receptor 763
olfactory receptor family 4 subfamily F member 4B
olfactory receptor gene Olr763

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    118551424..118555594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039106584.1XP_038962512.1  olfactory receptor 4F4

    UniProtKB/TrEMBL
    F1LT92
    Conserved Domains (1) summary
    cd15226
    Location:95351
    7tmA_OR4-like; olfactory receptor family 4 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors