U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

IGKV1-39 immunoglobulin kappa variable 1-39 [ Homo sapiens (human) ]

Gene ID: 28930, updated on 23-Nov-2023

Summary

Official Symbol
IGKV1-39provided by HGNC
Official Full Name
immunoglobulin kappa variable 1-39provided by HGNC
Primary source
HGNC:HGNC:5740
See related
Ensembl:ENSG00000242371 IMGT/GENE-DB:IGKV1-39; AllianceGenome:HGNC:5740
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
O12; O12a; IGKV139
Summary
Predicted to be involved in immune response. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See IGKV1-39 in Genome Data Viewer
Location:
2p11.2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (89319625..89320099, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (89328963..89329437, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (89619383..89619857, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa locus Neighboring gene immunoglobulin kappa variable 1-37 (non-functional) Neighboring gene immunoglobulin kappa variable 2-38 (pseudogene) Neighboring gene immunoglobulin kappa variable 2-40 Neighboring gene proton channel OTOP1-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:91799900-91800404

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • Ig kappa chain V-I region DEE

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables antigen binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in immune response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in immunoglobulin production IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in blood microparticle HDA PubMed 
located_in extracellular exosome HDA PubMed 
located_in extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of immunoglobulin complex IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_000834.1 

    Range
    21528..22002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    89319625..89320099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132915.1 Reference GRCh38.p14 PATCHES

    Range
    428451..428925 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    89328963..89329437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)