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ALKAL2 ALK and LTK ligand 2 [ Homo sapiens (human) ]

Gene ID: 285016, updated on 23-Nov-2021

Summary

Official Symbol
ALKAL2provided by HGNC
Official Full Name
ALK and LTK ligand 2provided by HGNC
Primary source
HGNC:HGNC:27683
See related
Ensembl:ENSG00000189292
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AUGA; FAM150B; PRO1097; RGPG542
Expression
Biased expression in adrenal (RPKM 46.6), ovary (RPKM 14.2) and 6 other tissues See more
Orthologs
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Genomic context

See ALKAL2 in Genome Data Viewer
Location:
2p25.3
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (279558..288872, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (279558..288091, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene SH3 and SYLF domain containing 1 Neighboring gene acid phosphatase 1 Neighboring gene uncharacterized LOC101927262 Neighboring gene uncharacterized LOC105373346 Neighboring gene long intergenic non-protein coding RNA 1865

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
ALK and LTK ligand 2
Names
AUG-alpha
augmentor alpha
augmentor-beta
family with sequence similarity 150 member B
protein FAM150B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002919.3NP_001002919.2  ALK and LTK ligand 2 precursor

    See identical proteins and their annotated locations for NP_001002919.2

    Status: VALIDATED

    Source sequence(s)
    AC079779, AI300876, BC033490
    Consensus CDS
    CCDS46218.1
    UniProtKB/Swiss-Prot
    Q6UX46
    Related
    ENSP00000384604.3, ENST00000403610.9
    Conserved Domains (1) summary
    pfam15129
    Location:35149
    FAM150; FAM150 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    279558..288872 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510342.3XP_011508644.1  ALK and LTK ligand 2 isoform X3

    Conserved Domains (1) summary
    pfam15129
    Location:35122
    FAM150; FAM150 family
  2. XM_006711879.4XP_006711942.1  ALK and LTK ligand 2 isoform X2

    See identical proteins and their annotated locations for XP_006711942.1

    UniProtKB/TrEMBL
    A0A0B4J1W8
    Related
    ENSP00000389939.1, ENST00000452023.1
    Conserved Domains (1) summary
    pfam15129
    Location:35149
    FAM150; FAM150 family
  3. XM_005264689.5XP_005264746.1  ALK and LTK ligand 2 isoform X1

    See identical proteins and their annotated locations for XP_005264746.1

    UniProtKB/Swiss-Prot
    Q6UX46
    Conserved Domains (1) summary
    pfam15129
    Location:35149
    FAM150; FAM150 family
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