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OR2L13 olfactory receptor family 2 subfamily L member 13 [ Homo sapiens (human) ]

Gene ID: 284521, updated on 1-Aug-2020

Summary

Official Symbol
OR2L13provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily L member 13provided by HGNC
Primary source
HGNC:HGNC:19578
See related
Ensembl:ENSG00000196071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2L14
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See OR2L13 in Genome Data Viewer
Location:
1q44
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (247937029..248100922)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248100493..248264224)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 8 Neighboring gene olfactory receptor family 2 subfamily AJ member 1 Neighboring gene CDC like kinase 3 pseudogene 2 Neighboring gene olfactory receptor family 2 subfamily X member 1 pseudogene Neighboring gene olfactory receptor family 2 subfamily L member 8 Neighboring gene olfactory receptor family 2 subfamily AK member 2 Neighboring gene olfactory receptor family 2 subfamily L member 9 pseudogene Neighboring gene olfactory receptor family 2 subfamily L member 1 pseudogene Neighboring gene olfactory receptor family 2 subfamily L member 6 pseudogene Neighboring gene olfactory receptor family 2 subfamily L member 5 Neighboring gene uncharacterized LOC105373275 Neighboring gene olfactory receptor family 2 subfamily L member 2 Neighboring gene olfactory receptor family 2 subfamily L member 3 Neighboring gene olfactory receptor family 2 subfamily T member 32 pseudogene Neighboring gene olfactory receptor family 2 subfamily M member 1 pseudogene Neighboring gene olfactory receptor family 2 subfamily M member 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC40047

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
biological_process ND
No biological Data available
more info
 
detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2L13
Names
olfactory receptor 2L14
olfactory receptor, family 2, subfamily L, member 14

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304535.1NP_001291464.1  olfactory receptor 2L13

    See identical proteins and their annotated locations for NP_001291464.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC099571, AL513488
    Consensus CDS
    CCDS1637.1
    UniProtKB/Swiss-Prot
    Q8N349
    UniProtKB/TrEMBL
    A0A126GW96
    Related
    ENSP00000492949.1, ENST00000641893.1
    Conserved Domains (1) summary
    cd15421
    Location:37300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_175911.3NP_787107.1  olfactory receptor 2L13

    See identical proteins and their annotated locations for NP_787107.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC099571, AL513488
    Consensus CDS
    CCDS1637.1
    UniProtKB/Swiss-Prot
    Q8N349
    UniProtKB/TrEMBL
    A0A126GW96
    Conserved Domains (1) summary
    cd15421
    Location:37300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    247937029..248100922
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544169.2XP_011542471.1  olfactory receptor 2L13 isoform X1

    See identical proteins and their annotated locations for XP_011542471.1

    UniProtKB/Swiss-Prot
    Q8N349
    UniProtKB/TrEMBL
    A0A126GW96
    Related
    ENSP00000350836.2, ENST00000358120.3
    Conserved Domains (1) summary
    cd15421
    Location:37300
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
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