U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ACTL9 actin like 9 [ Homo sapiens (human) ]

Gene ID: 284382, updated on 5-Aug-2022

Summary

Official Symbol
ACTL9provided by HGNC
Official Full Name
actin like 9provided by HGNC
Primary source
HGNC:HGNC:28494
See related
Ensembl:ENSG00000181786 MIM:619251; AllianceGenome:HGNC:28494
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSD21; SPGF53
Summary
Predicted to be located in cytoplasm. Predicted to be part of dynactin complex. Implicated in spermatogenic failure 53. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ACTL9 in Genome Data Viewer
Location:
19p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (8697400..8698795, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (8692998..8694393, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (8807750..8809145, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 10 Neighboring gene Sharpr-MPRA regulatory region 9055 Neighboring gene NFIL3 like basic leucine zipper Neighboring gene ribosomal protein L23a pseudogene 78 Neighboring gene olfactory receptor family 2 subfamily Z member 1 Neighboring gene zinc finger protein 558 Neighboring gene methyl-CpG binding domain protein 3 like 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Spermatogenic failure 53
MedGen: C5543253 OMIM: 619258 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC33407

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in acrosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fertilization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in single fertilization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in perinuclear theca IDA
Inferred from Direct Assay
more info
PubMed 
located_in sperm head IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
actin-like protein 9
Names
testicular tissue protein Li 15
testicular tissue protein Li 9

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178525.5NP_848620.3  actin-like protein 9

    See identical proteins and their annotated locations for NP_848620.3

    Status: VALIDATED

    Source sequence(s)
    AI798166, BC024028, HY011370, HY042660
    Consensus CDS
    CCDS12207.1
    UniProtKB/Swiss-Prot
    Q6X960, Q8TC94
    Related
    ENSP00000316674.3, ENST00000324436.5
    Conserved Domains (2) summary
    smart00268
    Location:49415
    ACTIN; Actin
    cl17037
    Location:49416
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    8697400..8698795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    8692998..8694393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)