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GPR20 G protein-coupled receptor 20 [ Homo sapiens (human) ]

Gene ID: 2843, updated on 22-Aug-2020

Summary

Official Symbol
GPR20provided by HGNC
Official Full Name
G protein-coupled receptor 20provided by HGNC
Primary source
HGNC:HGNC:4475
See related
Ensembl:ENSG00000204882 MIM:601908
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See GPR20 in Genome Data Viewer
Location:
8q24.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (141356470..141367286, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (142366585..142377365, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene solute carrier family 45 member 4 Neighboring gene uncharacterized LOC105375787 Neighboring gene long intergenic non-protein coding RNA 1300 Neighboring gene uncharacterized LOC101928037 Neighboring gene uncharacterized LOC105375790

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
receptor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
G-protein coupled receptor 20
Names
CTD-3064M3.3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005293.3NP_005284.2  G-protein coupled receptor 20

    See identical proteins and their annotated locations for NP_005284.2

    Status: VALIDATED

    Source sequence(s)
    AA601037, AB209066, AC100803, DR006873
    Consensus CDS
    CCDS34949.1
    UniProtKB/Swiss-Prot
    Q99678
    UniProtKB/TrEMBL
    Q59GP3
    Related
    ENSP00000366970.3, ENST00000377741.4
    Conserved Domains (1) summary
    pfam00001
    Location:71297
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    141356470..141367286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187574.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    23024..33840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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