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IGSF22 immunoglobulin superfamily member 22 [ Homo sapiens (human) ]

Gene ID: 283284, updated on 23-Nov-2021

Summary

Official Symbol
IGSF22provided by HGNC
Official Full Name
immunoglobulin superfamily member 22provided by HGNC
Primary source
HGNC:HGNC:26750
See related
Ensembl:ENSG00000179057
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGFN2
Expression
Broad expression in kidney (RPKM 2.8), skin (RPKM 1.7) and 21 other tissues See more
Orthologs
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Genomic context

See IGSF22 in Genome Data Viewer
Location:
11p15.1
Exon count:
23
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (18704311..18726939, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (18725859..18747735, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376578 Neighboring gene SRSF3 pseudogene 1 Neighboring gene uncharacterized LOC105376579 Neighboring gene transmembrane protein 86A Neighboring gene protein tyrosine phosphatase non-receptor type 5 Neighboring gene Sharpr-MPRA regulatory region 5421 Neighboring gene MAS related GPR family member X8, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ37794

General protein information

Preferred Names
immunoglobulin superfamily member 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173588.4NP_775859.4  immunoglobulin superfamily member 22

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AC103974
    Consensus CDS
    CCDS41625.2
    Related
    ENSP00000421191.1, ENST00000513874.6

RNA

  1. NR_160413.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC103974
    Related
    ENST00000319338.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    18704311..18726939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017607.1XP_016873096.1  immunoglobulin superfamily member 22 isoform X1

    Conserved Domains (6) summary
    cd00096
    Location:456512
    Ig; Immunoglobulin domain
    cd05748
    Location:647717
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    smart00410
    Location:637717
    IG_like; Immunoglobulin like
    cd00063
    Location:822912
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:12331322
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:12561322
    Ig; Immunoglobulin domain
  2. XM_017017608.1XP_016873097.1  immunoglobulin superfamily member 22 isoform X3

    UniProtKB/Swiss-Prot
    Q8N9C0
  3. XM_011520031.2XP_011518333.1  immunoglobulin superfamily member 22 isoform X2

    Conserved Domains (6) summary
    cd00096
    Location:456512
    Ig; Immunoglobulin domain
    cd05748
    Location:647717
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    smart00410
    Location:637717
    IG_like; Immunoglobulin like
    cd00063
    Location:721811
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:11321221
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:11551221
    Ig; Immunoglobulin domain
  4. XM_011520030.2XP_011518332.1  immunoglobulin superfamily member 22 isoform X1

    Conserved Domains (6) summary
    cd00096
    Location:456512
    Ig; Immunoglobulin domain
    cd05748
    Location:647717
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    smart00410
    Location:637717
    IG_like; Immunoglobulin like
    cd00063
    Location:822912
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:12331322
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:12561322
    Ig; Immunoglobulin domain
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