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NPBWR1 neuropeptides B and W receptor 1 [ Homo sapiens (human) ]

Gene ID: 2831, updated on 8-Jul-2021

Summary

Official Symbol
NPBWR1provided by HGNC
Official Full Name
neuropeptides B and W receptor 1provided by HGNC
Primary source
HGNC:HGNC:4522
See related
Ensembl:ENSG00000288611 MIM:600730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPR7
Orthologs
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Genomic context

See NPBWR1 in Genome Data Viewer
Location:
8q11.23
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (52939182..52943734)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (53851742..53856294)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375835 Neighboring gene uncharacterized LOC107986943 Neighboring gene E3 ubiquitin-protein ligase RING2-like Neighboring gene uncharacterized LOC105375836 Neighboring gene EI24 pseudogene 5

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129755

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled opioid receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neuropeptide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neuropeptide receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IC
Inferred by Curator
more info
PubMed 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
neuropeptides B/W receptor type 1
Names
G-protein coupled receptor 7
neuropeptide B/W receptor 1
neuropeptides B/W receptor 1
opioid-somatostatin-like receptor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005285.5NP_005276.2  neuropeptides B/W receptor type 1

    See identical proteins and their annotated locations for NP_005276.2

    Status: VALIDATED

    Source sequence(s)
    AC087348
    Consensus CDS
    CCDS6151.1
    UniProtKB/Swiss-Prot
    P48145
    UniProtKB/TrEMBL
    H9NIL7
    Related
    ENSP00000501711.1, ENST00000674939.1
    Conserved Domains (1) summary
    cd15087
    Location:47318
    7tmA_NPBWR; neuropeptide B/W receptors, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    52939182..52943734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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