TMSB4X thymosin beta 4 X-linked [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: TMSB4X
Gene description: thymosin beta 4 X-linked
See related: BGD:BT29994; Ensembl:ENSBTAG00000038488
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	X	NC_037357.1 (130698922..130700970, complement)

Chromosome X - NC_037357.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tbeta4 induces apoptotic-related gene expression in leukemic cells, and results in the inhibition of proliferation and induction of differentiation and apoptosis of leukemic cells
Title: Thymosin beta4 and AcSDKP inhibit the proliferation of HL-60 cells and induce their differentiation and apoptosis.

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General gene information

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Markers

TMSB4X (e-PCR)
- UniSTS:506515

SSC10E06 (e-PCR)
- UniSTS:253357

MARC_4921-4922:991938931:1 (e-PCR)
- UniSTS:231122

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin monomer binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sequestering of actin monomers	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thymosin beta-4

Names: thymosin beta 4, X chromosome

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.