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Ip6k1 inositol hexaphosphate kinase 1 [ Mus musculus (house mouse) ]

Gene ID: 27399, updated on 1-Mar-2024

Summary

Official Symbol
Ip6k1provided by MGI
Official Full Name
inositol hexaphosphate kinase 1provided by MGI
Primary source
MGI:MGI:1351633
See related
Ensembl:ENSMUSG00000032594 AllianceGenome:MGI:1351633
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ihpk1; InsP6; Itpk6; InsP6k1; 1200016D08Rik
Summary
Predicted to enable inositol hexakisphosphate kinase activity. Involved in negative regulation of cold-induced thermogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Orthologous to human IP6K1 (inositol hexakisphosphate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 61.4), ovary adult (RPKM 49.6) and 28 other tissues See more
Orthologs
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Genomic context

See Ip6k1 in Genome Data Viewer
Location:
9 F1; 9 59.07 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (107879847..107925981)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (108002648..108048782)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene inka box actin regulator 1 Neighboring gene RIKEN cDNA 4930535L15 gene Neighboring gene cadherin-related family member 4 Neighboring gene STARR-positive B cell enhancer ABC_E61 Neighboring gene STARR-positive B cell enhancer ABC_E2305 Neighboring gene STARR-positive B cell enhancer ABC_E6803 Neighboring gene STARR-positive B cell enhancer ABC_E3859 Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene ring finger protein 123 Neighboring gene adhesion molecule with Ig like domain 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: Cdhr4

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables inositol hexakisphosphate 1-kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables inositol hexakisphosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables inositol hexakisphosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables inositol hexakisphosphate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables inositol hexakisphosphate kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables inositol-1,3,4,5,6-pentakisphosphate kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
inositol hexakisphosphate kinase 1
Names
inositol hexakisphosphate kinase 6
insP6 kinase 1
NP_038813.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013785.2NP_038813.2  inositol hexakisphosphate kinase 1

    See identical proteins and their annotated locations for NP_038813.2

    Status: PROVISIONAL

    Source sequence(s)
    BC059006
    Consensus CDS
    CCDS23514.1
    UniProtKB/Swiss-Prot
    Q6PD10, Q9QXV6
    UniProtKB/TrEMBL
    Q6A097
    Related
    ENSMUSP00000035214.5, ENSMUST00000035214.11
    Conserved Domains (1) summary
    pfam03770
    Location:207426
    IPK; Inositol polyphosphate kinase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    107879847..107925981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_026266.1: Suppressed sequence

    Description
    NM_026266.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.