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Rpl3 ribosomal protein L3 [ Mus musculus (house mouse) ]

Gene ID: 27367, updated on 26-Sep-2022

Summary

Official Symbol
Rpl3provided by MGI
Official Full Name
ribosomal protein L3provided by MGI
Primary source
MGI:MGI:1351605
See related
Ensembl:ENSMUSG00000060036 AllianceGenome:MGI:1351605
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
F2; J1
Summary
Predicted to enable 5S rRNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within cellular response to interleukin-4. Predicted to be located in cytosolic ribosome and nucleolus. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in early conceptus. Orthologous to human RPL3 (ribosomal protein L3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 486.3), liver E14 (RPKM 380.2) and 28 other tissues See more
Orthologs
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Genomic context

See Rpl3 in Genome Data Viewer
Location:
15; 15 E1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79961982..79967607, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (80077781..80083406, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41361 Neighboring gene predicted gene, 53904 Neighboring gene predicted gene, 41362 Neighboring gene small nucleolar RNA U82P Neighboring gene small nucleolar RNA, C/D box 83B Neighboring gene small nucleolar RNA, C/D box 43 Neighboring gene predicted gene, 24204 Neighboring gene predicted gene, 31134 Neighboring gene synaptogyrin 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC103388

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 5S rRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to interleukin-4 IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cytoplasmic translation IC
Inferred by Curator
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IC
Inferred by Curator
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
60S ribosomal protein L3
Names
ribosomal protein L3 homolog
NP_038790.2
XP_006521099.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013762.3NP_038790.2  60S ribosomal protein L3

    See identical proteins and their annotated locations for NP_038790.2

    Status: VALIDATED

    Source sequence(s)
    AC161199
    Consensus CDS
    CCDS37144.1
    UniProtKB/Swiss-Prot
    P27659, Q91VJ6
    UniProtKB/TrEMBL
    A0A8C6ID79
    Related
    ENSMUSP00000080354.8, ENSMUST00000081650.15
    Conserved Domains (1) summary
    PTZ00103
    Location:1400
    PTZ00103; 60S ribosomal protein L3; Provisional

RNA

  1. NR_177964.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC161199

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    79961982..79967607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521036.3XP_006521099.1  60S ribosomal protein L3 isoform X1

    Conserved Domains (1) summary
    PTZ00103
    Location:1248
    PTZ00103; 60S ribosomal protein L3; Provisional