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ARFIP1 ADP ribosylation factor interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 27236, updated on 24-Nov-2021

Summary

Official Symbol
ARFIP1provided by HGNC
Official Full Name
ADP ribosylation factor interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:21496
See related
Ensembl:ENSG00000164144 MIM:605928
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSU52521
Expression
Ubiquitous expression in gall bladder (RPKM 8.9), colon (RPKM 8.5) and 25 other tissues See more
Orthologs
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Genomic context

See ARFIP1 in Genome Data Viewer
Location:
4q31.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (152779954..152912357)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (153701106..153833509)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377495 Neighboring gene tigger transposable element derived 4 Neighboring gene NSA2 pseudogene 6 Neighboring gene Sharpr-MPRA regulatory region 8200 Neighboring gene family with sequence similarity 192, member A pseudogene Neighboring gene uncharacterized LOC729870 Neighboring gene FH2 domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC117369

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol-4-phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in trans-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in trans-Golgi network membrane IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025593.3NP_001020764.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_001020764.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AC099339, AI634366, AK096509, AK299600, AK304141, BC103759, BC105114
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000348360.3, ENST00000356064.3
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  2. NM_001025595.3NP_001020766.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001020766.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 4, and 5 encode the same isoform.
    Source sequence(s)
    AC099339, AI634366, AK096509, AK299600, AK304141, BC103759, BC105114, DC346238
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000296557.4, ENST00000353617.7
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  3. NM_001287431.2NP_001274360.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001274360.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AC099339, AI634366, AK096509, AK299600, AK304141, BC103759
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000395083.2, ENST00000451320.6
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  4. NM_001287432.2NP_001274361.1  arfaptin-1 isoform 1

    See identical proteins and their annotated locations for NP_001274361.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AC099339, AI634366, AK096509, AK299600, AK304141, AU139844, BC103759, BC105114
    Consensus CDS
    CCDS34080.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Conserved Domains (1) summary
    cd07660
    Location:155355
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  5. NM_001287433.2NP_001274362.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_001274362.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AC099339, AI634366, AK096509, AK299600, AK304141, BC103759, BC105114, DA452239
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
  6. NM_014447.4NP_055262.1  arfaptin-1 isoform 2

    See identical proteins and their annotated locations for NP_055262.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Variants 2, 3, and 6 encode the same isoform.
    Source sequence(s)
    AC099339, AI634366, AK096509, AK290472, AK299600, AK304141
    Consensus CDS
    CCDS3780.1
    UniProtKB/Swiss-Prot
    P53367
    UniProtKB/TrEMBL
    B4E273, Q8N8M9
    Related
    ENSP00000384189.2, ENST00000405727.6
    Conserved Domains (1) summary
    cd07660
    Location:123323
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    152779954..152912357
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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