Format

Send to:

Choose Destination

GHITM growth hormone inducible transmembrane protein [ Homo sapiens (human) ]

Gene ID: 27069, updated on 13-Mar-2020

Summary

Official Symbol
GHITMprovided by HGNC
Official Full Name
growth hormone inducible transmembrane proteinprovided by HGNC
Primary source
HGNC:HGNC:17281
See related
Ensembl:ENSG00000165678
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282
Expression
Ubiquitous expression in heart (RPKM 139.5), kidney (RPKM 133.1) and 25 other tissues See more
Orthologs

Genomic context

See GHITM in Genome Data Viewer
Location:
10q23.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (84139509..84153568)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (85899185..85913311)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378399 Neighboring gene RNA, U1 small nuclear 65, pseudogene Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 8 Neighboring gene competing endogenous lncRNA 2 for microRNA let-7b Neighboring gene chromosome 10 open reading frame 99

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ26584, DKFZp566C0746

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
growth hormone-inducible transmembrane protein
Names
dermal papilla-derived protein 2
mitochondrial morphology and cristae structure 1
transmembrane BAX inhibitor motif containing 5
transmembrane BAX inhibitor motif-containing protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014394.3NP_055209.2  growth hormone-inducible transmembrane protein

    See identical proteins and their annotated locations for NP_055209.2

    Status: VALIDATED

    Source sequence(s)
    AC022389, AL603756, BC010354
    Consensus CDS
    CCDS41542.1
    UniProtKB/Swiss-Prot
    Q9H3K2
    Related
    ENSP00000361207.3, ENST00000372134.6
    Conserved Domains (1) summary
    cd10431
    Location:81344
    GHITM; Growth-hormone inducible transmembrane protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    84139509..84153568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center