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UTP25 UTP25 small subunit processome component [ Homo sapiens (human) ]

Gene ID: 27042, updated on 6-Sep-2022

Summary

Official Symbol
UTP25provided by HGNC
Official Full Name
UTP25 small subunit processome componentprovided by HGNC
Primary source
HGNC:HGNC:28440
See related
Ensembl:ENSG00000117597 MIM:619663; AllianceGenome:HGNC:28440
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DEF; DIEXF; C1orf107; DJ434O14.5
Summary
Enables RNA binding activity. Involved in several processes, including protein catabolic process; protein destabilization; and protein localization to nucleolus. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 3.8), thyroid (RPKM 2.8) and 25 other tissues See more
Orthologs
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Genomic context

See UTP25 in Genome Data Viewer
Location:
1q32.2
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (209827972..209857565)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (209074743..209104338)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (210001317..210030910)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs932 Neighboring gene interferon regulatory factor 6 Neighboring gene Sharpr-MPRA regulatory region 1786 Neighboring gene Sharpr-MPRA regulatory region 13960 Neighboring gene synaptotagmin 14

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12704, FLJ41680, MGC29875, DKFZp686E19106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables U3 snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
U3 small nucleolar RNA-associated protein 25 homolog
Names
UTP25 small subunit processor component
digestive-organ expansion factor homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014388.7NP_055203.4  U3 small nucleolar RNA-associated protein 25 homolog

    See identical proteins and their annotated locations for NP_055203.4

    Status: VALIDATED

    Source sequence(s)
    AL022398, AL022728, BC022964, CR749825, DA256510
    Consensus CDS
    CCDS1493.1
    UniProtKB/Swiss-Prot
    Q63HL9, Q68CQ4
    Related
    ENSP00000419005.1, ENST00000491415.7
    Conserved Domains (1) summary
    pfam06862
    Location:276751
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    209827972..209857565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006711275.4XP_006711338.1  U3 small nucleolar RNA-associated protein 25 homolog isoform X1

    Conserved Domains (1) summary
    pfam06862
    Location:276561
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    209074743..209104338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)