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UTP25 UTP25 small subunit processor component [ Homo sapiens (human) ]

Gene ID: 27042, updated on 7-Jun-2020

Summary

Official Symbol
UTP25provided by HGNC
Official Full Name
UTP25 small subunit processor componentprovided by HGNC
Primary source
HGNC:HGNC:28440
See related
Ensembl:ENSG00000117597
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DEF; DIEXF; C1orf107; DJ434O14.5
Expression
Ubiquitous expression in ovary (RPKM 3.8), thyroid (RPKM 2.8) and 25 other tissues See more
Orthologs

Genomic context

See UTP25 in Genome Data Viewer
Location:
1q32.2
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (209827972..209857565)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (210001312..210030910)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs932 Neighboring gene interferon regulatory factor 6 Neighboring gene Sharpr-MPRA regulatory region 13960 Neighboring gene synaptotagmin 14

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12704, FLJ41680, MGC29875, DKFZp686E19106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
U3 snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of embryonic development ISS
Inferred from Sequence or Structural Similarity
more info
 
protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein destabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA processing TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
digestive organ expansion factor homolog
Names
digestive-organ expansion factor homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014388.7NP_055203.4  digestive organ expansion factor homolog

    See identical proteins and their annotated locations for NP_055203.4

    Status: VALIDATED

    Source sequence(s)
    AL022398, AL022728, BC022964, CR749825, DA256510
    Consensus CDS
    CCDS1493.1
    UniProtKB/Swiss-Prot
    Q68CQ4
    Related
    ENSP00000419005.1, ENST00000491415.7
    Conserved Domains (1) summary
    pfam06862
    Location:276751
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    209827972..209857565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006711275.4XP_006711338.1  digestive organ expansion factor homolog isoform X1

    Conserved Domains (1) summary
    pfam06862
    Location:276561
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
  2. XM_011509418.3XP_011507720.1  digestive organ expansion factor homolog isoform X2

    Conserved Domains (1) summary
    pfam06862
    Location:1466
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
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