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SMR3A submaxillary gland androgen regulated protein 3A [ Homo sapiens (human) ]

Gene ID: 26952, updated on 13-Mar-2020

Summary

Official Symbol
SMR3Aprovided by HGNC
Official Full Name
submaxillary gland androgen regulated protein 3Aprovided by HGNC
Primary source
HGNC:HGNC:19216
See related
Ensembl:ENSG00000109208 MIM:618340
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PBI; P-B1; PRL5; PROL5
Expression
Restricted expression toward salivary gland (RPKM 1417.1) See more
Orthologs

Genomic context

See SMR3A in Genome Data Viewer
Location:
4q13.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (70360760..70367158)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (71226493..71232823)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene casein kappa Neighboring gene calcium binding protein, spermatid associated 1 Neighboring gene submaxillary gland androgen regulated protein 3B Neighboring gene opiorphin prepropeptide

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
regulation of sensory perception of pain IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
submaxillary gland androgen-regulated protein 3A
Names
proline rich 5 (salivary)
proline- rich protein 5
proline-rich protein PBI
protein homologous to salivary proline-rich protein P-B
submaxillary gland androgen regulated protein 3 homolog A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012390.4NP_036522.3  submaxillary gland androgen-regulated protein 3A precursor

    See identical proteins and their annotated locations for NP_036522.3

    Status: VALIDATED

    Source sequence(s)
    AC106884, CA946421, CD722957
    Consensus CDS
    CCDS34000.1
    UniProtKB/Swiss-Prot
    Q99954
    Related
    ENSP00000226460.4, ENST00000226460.5
    Conserved Domains (1) summary
    pfam15621
    Location:163
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    70360760..70367158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008021.1XP_016863510.1  submaxillary gland androgen-regulated protein 3A isoform X1

    UniProtKB/Swiss-Prot
    Q99954
    Conserved Domains (1) summary
    pfam15621
    Location:163
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
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