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Nbeal1 neurobeachin like 1 [ Mus musculus (house mouse) ]

Gene ID: 269198, updated on 26-Sep-2022

Summary

Official Symbol
Nbeal1provided by MGI
Official Full Name
neurobeachin like 1provided by MGI
Primary source
MGI:MGI:2444343
See related
Ensembl:ENSMUSG00000073664 AllianceGenome:MGI:2444343
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ALS2CR17; 2310076G13Rik; A530050O19Rik; A530083I02Rik
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytosol and membrane. Orthologous to human NBEAL1 (neurobeachin like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 3.9), CNS E18 (RPKM 1.7) and 25 other tissues See more
Orthologs
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Genomic context

See Nbeal1 in Genome Data Viewer
Location:
1; 1 C2
Exon count:
62
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (60217910..60377487)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (60178740..60338328)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 12 Neighboring gene predicted gene 15464 Neighboring gene calcium response factor Neighboring gene protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) pseudogene Neighboring gene cytochrome P450, family 20, subfamily a, polypeptide 1 Neighboring gene abl interactor 2 Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
neurobeachin-like protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173444.2NP_775620.2  neurobeachin-like protein 1

    Status: VALIDATED

    Source sequence(s)
    AC158139, AK040951, AK143706, BC060141, BQ550685
    Consensus CDS
    CCDS48274.1
    UniProtKB/TrEMBL
    E9PYP2, Q8BS04
    Related
    ENSMUSP00000124056.2, ENSMUST00000160834.8
    Conserved Domains (6) summary
    cd01201
    Location:18811978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24392484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:19992278
    Beach; Beige/BEACH domain
    pfam15787
    Location:8591129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:15751828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24032676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    60217910..60377487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496030.5XP_006496093.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496093.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006496033.5XP_006496096.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496096.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_006496032.5XP_006496095.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496095.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_006496035.4XP_006496098.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496098.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_030254693.1XP_030110553.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:18811978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24392484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:19992278
    Beach; Beige/BEACH domain
    pfam15787
    Location:8591129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:15751828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24032676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. XM_006496038.5XP_006496101.1  neurobeachin-like protein 1 isoform X5

    Conserved Domains (3) summary
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    pfam15787
    Location:8881158
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
  7. XM_030254697.2XP_030110557.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:17311828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:22892334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:18492128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:14251678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:22532526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  8. XM_011238527.4XP_011236829.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011236829.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  9. XM_006496037.5XP_006496100.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:17311828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:22892334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:18492128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:14251678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:22532526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  10. XM_030254700.2XP_030110560.1  neurobeachin-like protein 1 isoform X4

    Conserved Domains (6) summary
    cd01201
    Location:17021799
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:22602305
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:18202099
    Beach; Beige/BEACH domain
    pfam15787
    Location:680950
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:13961649
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:22242497
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  11. XM_006496029.4XP_006496092.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496092.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  12. XM_006496034.4XP_006496097.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496097.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  13. XM_030254692.2XP_030110552.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:18811978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24392484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:19992278
    Beach; Beige/BEACH domain
    pfam15787
    Location:8591129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:15751828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24032676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  14. XM_030254694.2XP_030110554.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:17311828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:22892334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:18492128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:14251678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:22532526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  15. XM_030254696.2XP_030110556.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:17311828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:22892334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:18492128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:14251678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:22532526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  16. XM_006496028.5XP_006496091.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496091.1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  17. XM_030254689.2XP_030110549.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:18811978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24392484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:19992278
    Beach; Beige/BEACH domain
    pfam15787
    Location:8591129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:15751828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24032676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  18. XM_036165459.1XP_036021352.1  neurobeachin-like protein 1 isoform X1

    Conserved Domains (6) summary
    smart01026
    Location:20272307
    Beach; Beige/BEACH domain
    cd01201
    Location:19102007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:24682513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:8881152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:16041857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:24322705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...